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Do symptomatic endometriosis and uterine fibroids appear together?

OBJECTIVES: Endometriosis and uterine fibroids are common gynecological disorders in fertile women. It has been suggested that these two disorders may be associated with each other. In this study, we tested whether this connection exists. In addition, we wanted to evaluate whether they both affect f...

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Autores principales: Uimari, Outi, Järvelä, Ilkka, Ryynänen, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136067/
https://www.ncbi.nlm.nih.gov/pubmed/21772738
http://dx.doi.org/10.4103/0974-1208.82358
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author Uimari, Outi
Järvelä, Ilkka
Ryynänen, Markku
author_facet Uimari, Outi
Järvelä, Ilkka
Ryynänen, Markku
author_sort Uimari, Outi
collection PubMed
description OBJECTIVES: Endometriosis and uterine fibroids are common gynecological disorders in fertile women. It has been suggested that these two disorders may be associated with each other. In this study, we tested whether this connection exists. In addition, we wanted to evaluate whether they both affect fertility independently of each other. MATERIALS AND METHODS: The prevalence of endometriosis and uterine fibroids was investigated in three groups of patients: Symptomatic patients requiring surgery either for endometriosis (n=182), or for uterine fibroids (n=240) and asymptomatic patients undergoing laparoscopic sterilization (n=183). The prevalences were examined in three age groups: 35–39 yrs, 40–44 yrs and ≥ 45 yrs. The significance of both diagnoses on fertility was assessed using logistic regression analysis. RESULTS: Uterine fibroids were detected in 25.8% (47/182) of patients with endometriosis. Endometriosis was detected in 19.6% (47/240) of patients with uterine fibroids. 5.5% (10/183) women undergoing sterilization had endometriosis and 19.3% (17/183) had uterine fibroids. Both uterine fibroids and endometriosis were, independently of each other, related to subfertility (OR, 95% CI: 3.8, 2.3–6.5; 6.8, 4.0–11.6, respectively). CONCLUSIONS: The results suggest that symptomatic endometriosis appears together with symptomatic uterine fibroids. Both diseases seem to decrease female fertility independently of each other.
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spelling pubmed-31360672011-07-19 Do symptomatic endometriosis and uterine fibroids appear together? Uimari, Outi Järvelä, Ilkka Ryynänen, Markku J Hum Reprod Sci Original Article OBJECTIVES: Endometriosis and uterine fibroids are common gynecological disorders in fertile women. It has been suggested that these two disorders may be associated with each other. In this study, we tested whether this connection exists. In addition, we wanted to evaluate whether they both affect fertility independently of each other. MATERIALS AND METHODS: The prevalence of endometriosis and uterine fibroids was investigated in three groups of patients: Symptomatic patients requiring surgery either for endometriosis (n=182), or for uterine fibroids (n=240) and asymptomatic patients undergoing laparoscopic sterilization (n=183). The prevalences were examined in three age groups: 35–39 yrs, 40–44 yrs and ≥ 45 yrs. The significance of both diagnoses on fertility was assessed using logistic regression analysis. RESULTS: Uterine fibroids were detected in 25.8% (47/182) of patients with endometriosis. Endometriosis was detected in 19.6% (47/240) of patients with uterine fibroids. 5.5% (10/183) women undergoing sterilization had endometriosis and 19.3% (17/183) had uterine fibroids. Both uterine fibroids and endometriosis were, independently of each other, related to subfertility (OR, 95% CI: 3.8, 2.3–6.5; 6.8, 4.0–11.6, respectively). CONCLUSIONS: The results suggest that symptomatic endometriosis appears together with symptomatic uterine fibroids. Both diseases seem to decrease female fertility independently of each other. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3136067/ /pubmed/21772738 http://dx.doi.org/10.4103/0974-1208.82358 Text en © Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Uimari, Outi
Järvelä, Ilkka
Ryynänen, Markku
Do symptomatic endometriosis and uterine fibroids appear together?
title Do symptomatic endometriosis and uterine fibroids appear together?
title_full Do symptomatic endometriosis and uterine fibroids appear together?
title_fullStr Do symptomatic endometriosis and uterine fibroids appear together?
title_full_unstemmed Do symptomatic endometriosis and uterine fibroids appear together?
title_short Do symptomatic endometriosis and uterine fibroids appear together?
title_sort do symptomatic endometriosis and uterine fibroids appear together?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136067/
https://www.ncbi.nlm.nih.gov/pubmed/21772738
http://dx.doi.org/10.4103/0974-1208.82358
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