An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans

Activation of melanocortin-4 receptor (MC4R) by insulin sensitive neurons is a central mechanism in body weight regulation, and genetic variants in the MC4R gene (e.g., rs17782313) are associated with obesity. By using magnetoencephalography, we addressed whether rs17782313 affects the cerebrocortic...

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Detalles Bibliográficos
Autores principales: Tschritter, Otto, Haupt, Axel, Preissl, Hubert, Ketterer, Caroline, Hennige, Anita M., Sartorius, Tina, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136179/
https://www.ncbi.nlm.nih.gov/pubmed/21773004
http://dx.doi.org/10.1155/2011/283153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136179/
https://www.ncbi.nlm.nih.gov/pubmed/21773004
http://dx.doi.org/10.1155/2011/283153

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