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Failure of CD4 T-Cells to Respond to Liver-Derived Antigen and to Provide Help to CD8 T-Cells

CD4 T-cell help is required for the induction of efficient CD8 T-cells responses and the generation of memory cells. Lack of CD4 T-cell help may contribute to an exhausted CD8 phenotype and viral persistence. Little is known about priming of CD4 T-cells by liver-derived antigen. We used TF-OVA mice...

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Detalles Bibliográficos
Autores principales:	Derkow, Katja, Müller, Anja, Eickmeier, Ira, Seidel, Daniel, Rust Moreira, Marcos Vicinius, Kruse, Nils, Klugewitz, Katja, Mintern, Justine, Wiedenmann, Bertram, Schott, Eckart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136477/ https://www.ncbi.nlm.nih.gov/pubmed/21779338 http://dx.doi.org/10.1371/journal.pone.0021847

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