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CD103 Deficiency Prevents Graft-versus-Host Disease but Spares Graft-versus-Tumor Effects Mediated by Alloreactive CD8 T Cells

BACKGROUND: Graft-versus-host disease (GVHD) remains the main barrier to broader application of allogeneic hematopoietic stem cell transplantation (alloSCT) as a curative therapy for host malignancy. GVHD is mediated by allogeneic T cells directed against histocompatibility antigens expressed by hos...

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Detalles Bibliográficos
Autores principales:	Liu, Kechang, Anthony, Bryan A., Yearsly, Martha M., Hamadani, Mehdi, Gaughan, Alice, Wang, Jiao-Jing, Devine, Steven M., Hadley, Gregg A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136479/ https://www.ncbi.nlm.nih.gov/pubmed/21779359 http://dx.doi.org/10.1371/journal.pone.0021968

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