Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood

BACKGROUND: Asthma exacerbations remain a major unmet clinical need. The difficulty in obtaining airway tissue and bronchoalveolar lavage samples during exacerbations has greatly hampered study of naturally occurring exacerbations. This study was conducted to determine if mRNA profiling of periphera...

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Detalles Bibliográficos
Autores principales: Bjornsdottir, Unnur S., Holgate, Stephen T., Reddy, Padmalatha S., Hill, Andrew A., McKee, Charlotte M., Csimma, Cristina I., Weaver, Amy A., Legault, Holly M., Small, Clayton G., Ramsey, Renee C., Ellis, Debra K., Burke, Conor M., Thompson, Philip J., Howarth, Peter H., Wardlaw, Andrew J., Bardin, Phillip G., Bernstein, David I., Irving, Louis B., Chupp, Geoffrey L., Bensch, George W., Bensch, Gregory W., Stahlman, Jon E., Karetzky, Monroe, Baker, James W., Miller, Rachel L., Goodman, Brad H., Raible, Donald G., Goldman, Samuel J., Miller, Douglas K., Ryan, John L., Dorner, Andrew J., Immermann, Frederick W., O'Toole, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136489/
https://www.ncbi.nlm.nih.gov/pubmed/21779351
http://dx.doi.org/10.1371/journal.pone.0021902

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