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An Intronic Variant in the GRP78, a Stress-Associated Gene, Improves Prediction for Liver Cirrhosis in Persistent HBV Carriers

BACKGROUND: Our previous study indicated that a common variant (rs430397 G>A) in the intron 5 of glucose-regulated protein 78 (GRP78) gene was associated with risk and prognosis of primary hepatocellular carcinoma (HCC), including HBV- and cirrhosis-related HCC. rs430397 polymorphism may be a con...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao, Chen, Lianzhou, Fan, Wenguo, Lin, Marie C. M., Tian, Linwei, Wang, Min, Lin, Sheng, Wang, Zifeng, Zhang, Jinfang, Wang, Jinlong, Yao, Hong, Kung, Hsiangfu, Li, Dongpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136490/
https://www.ncbi.nlm.nih.gov/pubmed/21779363
http://dx.doi.org/10.1371/journal.pone.0021997