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Smoking and COX-2 Functional Polymorphisms Interact to Increase the Risk of Gastric Cardia Adenocarcinoma in Chinese Population

BACKGROUND: Over-expression and increased activity of cyclooxygenase (COX)-2 induced by smoking has been implicated in the development of cancer. This study aimed to explore the interaction between smoking and functional polymorphisms of COX-2 in modulation of gastric cardia adenocarcinoma (GCA) ris...

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Detalles Bibliográficos
Autores principales: Zhang, Xue-Mei, Zhong, Rong, Liu, Li, Wang, Ying, Yuan, Ju-Xiang, Wang, Peng, Sun, Chuang, Zhang, Zhi, Song, Wen-Guang, Miao, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136492/
https://www.ncbi.nlm.nih.gov/pubmed/21779349
http://dx.doi.org/10.1371/journal.pone.0021894