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The Transcription Factor PU.1 Regulates γδ T Cell Homeostasis

BACKGROUND: T cell development results in the generation of both mature αβ and γδ T cells. While αβ T cells predominate in secondary lymphoid organs, γδ T cells are more abundant in mucosal tissues. PU.1, an Ets family transcription factor, also identified as the spleen focus forming virus proviral...

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Detalles Bibliográficos
Autores principales: Jabeen, Rukhsana, Chang, Hua-Chen, Goswami, Ritobrata, Nutt, Stephen L., Kaplan, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136513/
https://www.ncbi.nlm.nih.gov/pubmed/21779390
http://dx.doi.org/10.1371/journal.pone.0022189