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A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility

Gene-gene interactions are proposed as one important component of the genetic architecture of complex diseases, and are just beginning to be evaluated in the context of genome wide association studies (GWAS). In addition to detecting epistasis, a benefit to interaction analysis is that it also incre...

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Detalles Bibliográficos
Autores principales:	Bush, William S., McCauley, Jacob L., DeJager, Philip L., Dudek, Scott M., Hafler, David A., Gibson, Rachel A., Matthews, Paul M., Kappos, Ludwig, Naegelin, Yvonne, Polman, Chris H., Hauser, Stephen L., Oksenberg, Jorge, Haines, Jonathan L., Ritchie, Marylyn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136581/ https://www.ncbi.nlm.nih.gov/pubmed/21346779 http://dx.doi.org/10.1038/gene.2011.3

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