Cargando…

Withania somnifera Improves Semen Quality in Stress-Related Male Fertility

Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahdi, Abbas Ali, Shukla, Kamla Kant, Ahmad, Mohammad Kaleem, Rajender, Singh, Shankhwar, Satya Narain, Singh, Vishwajeet, Dalela, Deepansh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136684/
https://www.ncbi.nlm.nih.gov/pubmed/19789214
http://dx.doi.org/10.1093/ecam/nep138
_version_ 1782208230960660480
author Mahdi, Abbas Ali
Shukla, Kamla Kant
Ahmad, Mohammad Kaleem
Rajender, Singh
Shankhwar, Satya Narain
Singh, Vishwajeet
Dalela, Deepansh
author_facet Mahdi, Abbas Ali
Shukla, Kamla Kant
Ahmad, Mohammad Kaleem
Rajender, Singh
Shankhwar, Satya Narain
Singh, Vishwajeet
Dalela, Deepansh
author_sort Mahdi, Abbas Ali
collection PubMed
description Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients.
format Online
Article
Text
id pubmed-3136684
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-31366842011-07-26 Withania somnifera Improves Semen Quality in Stress-Related Male Fertility Mahdi, Abbas Ali Shukla, Kamla Kant Ahmad, Mohammad Kaleem Rajender, Singh Shankhwar, Satya Narain Singh, Vishwajeet Dalela, Deepansh Evid Based Complement Alternat Med Original Article Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients. Hindawi Publishing Corporation 2011 2011-06-18 /pmc/articles/PMC3136684/ /pubmed/19789214 http://dx.doi.org/10.1093/ecam/nep138 Text en Copyright © 2011 Abbas Ali Mahdi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mahdi, Abbas Ali
Shukla, Kamla Kant
Ahmad, Mohammad Kaleem
Rajender, Singh
Shankhwar, Satya Narain
Singh, Vishwajeet
Dalela, Deepansh
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title_full Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title_fullStr Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title_full_unstemmed Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title_short Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
title_sort withania somnifera improves semen quality in stress-related male fertility
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136684/
https://www.ncbi.nlm.nih.gov/pubmed/19789214
http://dx.doi.org/10.1093/ecam/nep138
work_keys_str_mv AT mahdiabbasali withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT shuklakamlakant withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT ahmadmohammadkaleem withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT rajendersingh withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT shankhwarsatyanarain withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT singhvishwajeet withaniasomniferaimprovessemenqualityinstressrelatedmalefertility
AT daleladeepansh withaniasomniferaimprovessemenqualityinstressrelatedmalefertility