Cargando…
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136684/ https://www.ncbi.nlm.nih.gov/pubmed/19789214 http://dx.doi.org/10.1093/ecam/nep138 |
_version_ | 1782208230960660480 |
---|---|
author | Mahdi, Abbas Ali Shukla, Kamla Kant Ahmad, Mohammad Kaleem Rajender, Singh Shankhwar, Satya Narain Singh, Vishwajeet Dalela, Deepansh |
author_facet | Mahdi, Abbas Ali Shukla, Kamla Kant Ahmad, Mohammad Kaleem Rajender, Singh Shankhwar, Satya Narain Singh, Vishwajeet Dalela, Deepansh |
author_sort | Mahdi, Abbas Ali |
collection | PubMed |
description | Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients. |
format | Online Article Text |
id | pubmed-3136684 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation
|
record_format | MEDLINE/PubMed |
spelling | pubmed-31366842011-07-26 Withania somnifera Improves Semen Quality in Stress-Related Male Fertility Mahdi, Abbas Ali Shukla, Kamla Kant Ahmad, Mohammad Kaleem Rajender, Singh Shankhwar, Satya Narain Singh, Vishwajeet Dalela, Deepansh Evid Based Complement Alternat Med Original Article Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients. Hindawi Publishing Corporation 2011 2011-06-18 /pmc/articles/PMC3136684/ /pubmed/19789214 http://dx.doi.org/10.1093/ecam/nep138 Text en Copyright © 2011 Abbas Ali Mahdi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mahdi, Abbas Ali Shukla, Kamla Kant Ahmad, Mohammad Kaleem Rajender, Singh Shankhwar, Satya Narain Singh, Vishwajeet Dalela, Deepansh Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title |
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title_full |
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title_fullStr |
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title_full_unstemmed |
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title_short |
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility |
title_sort | withania somnifera improves semen quality in stress-related male fertility |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136684/ https://www.ncbi.nlm.nih.gov/pubmed/19789214 http://dx.doi.org/10.1093/ecam/nep138 |
work_keys_str_mv | AT mahdiabbasali withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT shuklakamlakant withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT ahmadmohammadkaleem withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT rajendersingh withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT shankhwarsatyanarain withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT singhvishwajeet withaniasomniferaimprovessemenqualityinstressrelatedmalefertility AT daleladeepansh withaniasomniferaimprovessemenqualityinstressrelatedmalefertility |