PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses

Protein kinase C βII (PKCβII) levels increase in the myocardium of patients with end-stage heart failure (HF). Also targeted overexpression of PKCβII in the myocardium of mice leads to dilated cardiomyopathy associated with inflammation, fibrosis and myocardial dysfunction. These reports suggest a d...

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Detalles Bibliográficos
Autores principales: Palaniyandi, Suresh Selvaraj, Ferreira, Julio Cesar Batista, Brum, Patricia Chakur, Mochly-Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136735/
https://www.ncbi.nlm.nih.gov/pubmed/20874717
http://dx.doi.org/10.1111/j.1582-4934.2010.01174.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136735/
https://www.ncbi.nlm.nih.gov/pubmed/20874717
http://dx.doi.org/10.1111/j.1582-4934.2010.01174.x

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