DNA Vaccines against Dengue Virus Type 2 Based on Truncate Envelope Protein or Its Domain III

Two DNA vaccines were constructed encoding the ectodomain (domains I, II and III) of the DENV2 envelope protein (pE1D2) or only its domain III (pE2D2), fused to the human tissue plasminogen activator signal peptide (t-PA). The expression and secretion of recombinant proteins was confirmed in vitro i...

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Detalles Bibliográficos
Autores principales: Azevedo, Adriana S., Yamamura, Anna M. Y., Freire, Marcos S., Trindade, Gisela F., Bonaldo, Myrna, Galler, Ricardo, Alves, Ada M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136928/
https://www.ncbi.nlm.nih.gov/pubmed/21779317
http://dx.doi.org/10.1371/journal.pone.0020528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136928/
https://www.ncbi.nlm.nih.gov/pubmed/21779317
http://dx.doi.org/10.1371/journal.pone.0020528

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