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High Resolution Detection and Analysis of CpG Dinucleotides Methylation Using MBD-Seq Technology
Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA methylation patterns. However, the optimal experimental parameters for MBD-seq remain unclear and the data analysis remains challenging. In this study, we generated high depth MBD-seq data in MCF-7 cell and developed...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136941/ https://www.ncbi.nlm.nih.gov/pubmed/21779396 http://dx.doi.org/10.1371/journal.pone.0022226 |