CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer

Summary: Thousands of cancer exomes are currently being sequenced, yielding millions of non-synonymous single nucleotide variants (SNVs) of possible relevance to disease etiology. Here, we provide a software toolkit to prioritize SNVs based on their predicted contribution to tumorigenesis. It includ...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Wing Chung, Kim, Dewey, Carter, Hannah, Diekhans, Mark, Ryan, Michael C., Karchin, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137226/
https://www.ncbi.nlm.nih.gov/pubmed/21685053
http://dx.doi.org/10.1093/bioinformatics/btr357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137226/
https://www.ncbi.nlm.nih.gov/pubmed/21685053
http://dx.doi.org/10.1093/bioinformatics/btr357

Ejemplares similares