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CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer
Summary: Thousands of cancer exomes are currently being sequenced, yielding millions of non-synonymous single nucleotide variants (SNVs) of possible relevance to disease etiology. Here, we provide a software toolkit to prioritize SNVs based on their predicted contribution to tumorigenesis. It includ...
Autores principales: | Wong, Wing Chung, Kim, Dewey, Carter, Hannah, Diekhans, Mark, Ryan, Michael C., Karchin, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137226/ https://www.ncbi.nlm.nih.gov/pubmed/21685053 http://dx.doi.org/10.1093/bioinformatics/btr357 |
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