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Clinical implications of hedgehog signaling pathway inhibitors

Hedgehog was first described in Drosophila melanogaster by the Nobel laureates Eric Wieschaus and Christiane Nüsslein-Volhard. The hedgehog (Hh) pathway is a major regulator of cell differentiation, proliferation, tissue polarity, stem cell maintenance, and Carcinogenesis. The first link of Hh signa...

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Detalles Bibliográficos
Autores principales: Liu, Hailan, Gu, Dongsheng, Xie, Jingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137255/
https://www.ncbi.nlm.nih.gov/pubmed/21192841
http://dx.doi.org/10.5732/cjc.010.10540