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How to minimise the effect of tumour cell content in detection of aberrant genetic markers in neuroblastoma

BACKGROUND: Clinical heterogeneity reflects the complexity of genetic events associated with neuroblastoma (NB). To identify the status of all described genetic loci with possible prognostic interest, high-throughput approaches have been used, but only with tumour cell content >60%. In some tumou...

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Detalles Bibliográficos
Autores principales: Piqueras, M, Navarro, S, Cañete, A, Castel, V, Noguera, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137406/
https://www.ncbi.nlm.nih.gov/pubmed/21654680
http://dx.doi.org/10.1038/bjc.2011.188