Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency

The hypothalamic melanocortin system is unique among neuropeptide systems controlling energy homeostasis, in that both anorexigenic proopiomelanocortin (POMC)-derived and orexigenic Agouti related-peptide (AgRP)-derived ligands act at the same receptors, namely melanocortin 3 and 4 receptors (MC3/4R...

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Detalles Bibliográficos
Autores principales: Corander, Marcus P., Rimmington, Debra, Challis, Benjamin G., O'Rahilly, Stephen, Coll, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2011
Materias:
Energy Balance-Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137464/
https://www.ncbi.nlm.nih.gov/pubmed/21363936
http://dx.doi.org/10.1210/en.2010-1450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137464/
https://www.ncbi.nlm.nih.gov/pubmed/21363936
http://dx.doi.org/10.1210/en.2010-1450

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