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Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency

The hypothalamic melanocortin system is unique among neuropeptide systems controlling energy homeostasis, in that both anorexigenic proopiomelanocortin (POMC)-derived and orexigenic Agouti related-peptide (AgRP)-derived ligands act at the same receptors, namely melanocortin 3 and 4 receptors (MC3/4R...

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Detalles Bibliográficos
Autores principales:	Corander, Marcus P., Rimmington, Debra, Challis, Benjamin G., O'Rahilly, Stephen, Coll, Anthony P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2011
Materias:	Energy Balance-Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137464/ https://www.ncbi.nlm.nih.gov/pubmed/21363936 http://dx.doi.org/10.1210/en.2010-1450

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