Interleukin-11 Drives Early Lung Inflammation during Mycobacterium tuberculosis Infection in Genetically Susceptible Mice

IL-11 is multifunctional cytokine whose physiological role in the lungs during pulmonary tuberculosis (TB) is poorly understood. Here, using in vivo administration of specific antibodies against IL-11, we demonstrate for the first time that blocking IL-11 diminishes histopathology and neutrophilic i...

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Detalles Bibliográficos
Autores principales: Kapina, Marina A., Shepelkova, Galina S., Avdeenko, Vadim G., Guseva, Anna N., Kondratieva, Tatiana K., Evstifeev, Vladimir V., Apt, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137601/
https://www.ncbi.nlm.nih.gov/pubmed/21789190
http://dx.doi.org/10.1371/journal.pone.0021878

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