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The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits
The integrated analysis of genotypic and expression data for association with complex traits could identify novel genetic pathways involved in complex traits. We profiled 19,573 expression probes in Epstein-Barr virus-transformed lymphoblastoid cell lines (LCLs) from 299 twins and correlated these w...
Autores principales: | Min, Josine L., Taylor, Jennifer M., Richards, J. Brent, Watts, Tim, Pettersson, Fredrik H., Broxholme, John, Ahmadi, Kourosh R., Surdulescu, Gabriela L., Lowy, Ernesto, Gieger, Christian, Newton-Cheh, Chris, Perola, Markus, Soranzo, Nicole, Surakka, Ida, Lindgren, Cecilia M., Ragoussis, Jiannis, Morris, Andrew P., Cardon, Lon R., Spector, Tim D., Zondervan, Krina T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137612/ https://www.ncbi.nlm.nih.gov/pubmed/21789213 http://dx.doi.org/10.1371/journal.pone.0022070 |
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