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Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party
Novel methods and associated tools permitting individual identification in publicly accessible SNP databases have become a debatable issue. There is growing concern that current technical and ethical safeguards to protect the identities of donors could be insufficient. In the context of human embryo...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137773/ https://www.ncbi.nlm.nih.gov/pubmed/21279481 http://dx.doi.org/10.1007/s12015-010-9226-2 |
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author | Knoppers, Bartha M. Isasi, Rosario Benvenisty, Nissim Kim, Ock-Joo Lomax, Geoffrey Morris, Clive Murray, Thomas H. Lee, Eng Hin Perry, Margery Richardson, Genevra Sipp, Douglas Tanner, Klaus Wahlström, Jan de Wert, Guido Zeng, Fanyi |
author_facet | Knoppers, Bartha M. Isasi, Rosario Benvenisty, Nissim Kim, Ock-Joo Lomax, Geoffrey Morris, Clive Murray, Thomas H. Lee, Eng Hin Perry, Margery Richardson, Genevra Sipp, Douglas Tanner, Klaus Wahlström, Jan de Wert, Guido Zeng, Fanyi |
author_sort | Knoppers, Bartha M. |
collection | PubMed |
description | Novel methods and associated tools permitting individual identification in publicly accessible SNP databases have become a debatable issue. There is growing concern that current technical and ethical safeguards to protect the identities of donors could be insufficient. In the context of human embryonic stem cell research, there are no studies focusing on the probability that an hESC line donor could be identified by analyzing published SNP profiles and associated genotypic and phenotypic information. We present the International Stem Cell Forum (ISCF) Ethics Working Party’s Policy Statement on “Publishing SNP Genotypes of Human Embryonic Stem Cell Lines (hESC)”. The Statement prospectively addresses issues surrounding the publication of genotypic data and associated annotations of hESC lines in open access databases. It proposes a balanced approach between the goals of open science and data sharing with the respect for fundamental bioethical principles (autonomy, privacy, beneficence, justice and research merit and integrity). |
format | Online Article Text |
id | pubmed-3137773 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Humana Press Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-31377732011-08-26 Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party Knoppers, Bartha M. Isasi, Rosario Benvenisty, Nissim Kim, Ock-Joo Lomax, Geoffrey Morris, Clive Murray, Thomas H. Lee, Eng Hin Perry, Margery Richardson, Genevra Sipp, Douglas Tanner, Klaus Wahlström, Jan de Wert, Guido Zeng, Fanyi Stem Cell Rev Article Novel methods and associated tools permitting individual identification in publicly accessible SNP databases have become a debatable issue. There is growing concern that current technical and ethical safeguards to protect the identities of donors could be insufficient. In the context of human embryonic stem cell research, there are no studies focusing on the probability that an hESC line donor could be identified by analyzing published SNP profiles and associated genotypic and phenotypic information. We present the International Stem Cell Forum (ISCF) Ethics Working Party’s Policy Statement on “Publishing SNP Genotypes of Human Embryonic Stem Cell Lines (hESC)”. The Statement prospectively addresses issues surrounding the publication of genotypic data and associated annotations of hESC lines in open access databases. It proposes a balanced approach between the goals of open science and data sharing with the respect for fundamental bioethical principles (autonomy, privacy, beneficence, justice and research merit and integrity). Humana Press Inc 2011-01-29 2011 /pmc/articles/PMC3137773/ /pubmed/21279481 http://dx.doi.org/10.1007/s12015-010-9226-2 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Article Knoppers, Bartha M. Isasi, Rosario Benvenisty, Nissim Kim, Ock-Joo Lomax, Geoffrey Morris, Clive Murray, Thomas H. Lee, Eng Hin Perry, Margery Richardson, Genevra Sipp, Douglas Tanner, Klaus Wahlström, Jan de Wert, Guido Zeng, Fanyi Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title | Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title_full | Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title_fullStr | Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title_full_unstemmed | Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title_short | Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party |
title_sort | publishing snp genotypes of human embryonic stem cell lines: policy statement of the international stem cell forum ethics working party |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137773/ https://www.ncbi.nlm.nih.gov/pubmed/21279481 http://dx.doi.org/10.1007/s12015-010-9226-2 |
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