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Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 ...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137978/ https://www.ncbi.nlm.nih.gov/pubmed/21776380 http://dx.doi.org/10.1155/2011/890308 |
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author | Tang, Alice M. Sheehan, Heidi B. Jordan, Michael R. Duong, Dang Van Terrin, Norma Dong, Kimberly Lien, Trinh Thi Minh Trung, Nguyen Vu Wanke, Christine A. Hien, Nguyen Duc |
author_facet | Tang, Alice M. Sheehan, Heidi B. Jordan, Michael R. Duong, Dang Van Terrin, Norma Dong, Kimberly Lien, Trinh Thi Minh Trung, Nguyen Vu Wanke, Christine A. Hien, Nguyen Duc |
author_sort | Tang, Alice M. |
collection | PubMed |
description | We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART. |
format | Online Article Text |
id | pubmed-3137978 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-31379782011-07-20 Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam Tang, Alice M. Sheehan, Heidi B. Jordan, Michael R. Duong, Dang Van Terrin, Norma Dong, Kimberly Lien, Trinh Thi Minh Trung, Nguyen Vu Wanke, Christine A. Hien, Nguyen Duc AIDS Res Treat Research Article We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART. Hindawi Publishing Corporation 2011 2011-07-06 /pmc/articles/PMC3137978/ /pubmed/21776380 http://dx.doi.org/10.1155/2011/890308 Text en Copyright © 2011 Alice M. Tang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Tang, Alice M. Sheehan, Heidi B. Jordan, Michael R. Duong, Dang Van Terrin, Norma Dong, Kimberly Lien, Trinh Thi Minh Trung, Nguyen Vu Wanke, Christine A. Hien, Nguyen Duc Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title_full | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title_fullStr | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title_full_unstemmed | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title_short | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
title_sort | predictors of weight change in male hiv-positive injection drug users initiating antiretroviral therapy in hanoi, vietnam |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137978/ https://www.ncbi.nlm.nih.gov/pubmed/21776380 http://dx.doi.org/10.1155/2011/890308 |
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