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Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam

We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 ...

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Autores principales: Tang, Alice M., Sheehan, Heidi B., Jordan, Michael R., Duong, Dang Van, Terrin, Norma, Dong, Kimberly, Lien, Trinh Thi Minh, Trung, Nguyen Vu, Wanke, Christine A., Hien, Nguyen Duc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137978/
https://www.ncbi.nlm.nih.gov/pubmed/21776380
http://dx.doi.org/10.1155/2011/890308
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author Tang, Alice M.
Sheehan, Heidi B.
Jordan, Michael R.
Duong, Dang Van
Terrin, Norma
Dong, Kimberly
Lien, Trinh Thi Minh
Trung, Nguyen Vu
Wanke, Christine A.
Hien, Nguyen Duc
author_facet Tang, Alice M.
Sheehan, Heidi B.
Jordan, Michael R.
Duong, Dang Van
Terrin, Norma
Dong, Kimberly
Lien, Trinh Thi Minh
Trung, Nguyen Vu
Wanke, Christine A.
Hien, Nguyen Duc
author_sort Tang, Alice M.
collection PubMed
description We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART.
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spelling pubmed-31379782011-07-20 Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam Tang, Alice M. Sheehan, Heidi B. Jordan, Michael R. Duong, Dang Van Terrin, Norma Dong, Kimberly Lien, Trinh Thi Minh Trung, Nguyen Vu Wanke, Christine A. Hien, Nguyen Duc AIDS Res Treat Research Article We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART. Hindawi Publishing Corporation 2011 2011-07-06 /pmc/articles/PMC3137978/ /pubmed/21776380 http://dx.doi.org/10.1155/2011/890308 Text en Copyright © 2011 Alice M. Tang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tang, Alice M.
Sheehan, Heidi B.
Jordan, Michael R.
Duong, Dang Van
Terrin, Norma
Dong, Kimberly
Lien, Trinh Thi Minh
Trung, Nguyen Vu
Wanke, Christine A.
Hien, Nguyen Duc
Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title_full Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title_fullStr Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title_full_unstemmed Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title_short Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
title_sort predictors of weight change in male hiv-positive injection drug users initiating antiretroviral therapy in hanoi, vietnam
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137978/
https://www.ncbi.nlm.nih.gov/pubmed/21776380
http://dx.doi.org/10.1155/2011/890308
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