Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells

Phosphodiesterase 4D (PDE4D) is a member of the large superfamily of phosphodiesterases. PDE4D polymorphisms have been found to associate with ischemic stroke. Proliferation and migration of vascular smooth muscle cells (VSMCs) play a critical role in the pathogenesis of atherosclerosis. In this stu...

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Detalles Bibliográficos
Autores principales: Liu, Lin, Xu, Xiaowei, Li, Jiejie, Li, Xia, Sheng, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137982/
https://www.ncbi.nlm.nih.gov/pubmed/21776361
http://dx.doi.org/10.4061/2011/534257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137982/
https://www.ncbi.nlm.nih.gov/pubmed/21776361
http://dx.doi.org/10.4061/2011/534257

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