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Variables and Strategies in Development of Therapeutic Post-Transcriptional Gene Silencing Agents

Post-transcriptional gene silencing (PTGS) agents such as ribozymes, RNAi and antisense have substantial potential for gene therapy of human retinal degenerations. These technologies are used to knockdown a specific target RNA and its cognate protein. The disease target mRNA may be a mutant mRNA cau...

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Detalles Bibliográficos
Autores principales:	Sullivan, Jack M., Yau, Edwin H., Kolniak, Tiffany A., Sheflin, Lowell G., Taggart, R. Thomas, Abdelmaksoud, Heba E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138052/ https://www.ncbi.nlm.nih.gov/pubmed/21785698 http://dx.doi.org/10.1155/2011/531380

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