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Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock

The current consensus model for the circadian clock in mammals is based on a transcription-translation feedback loop. In this model, CRY and PER proteins repress their own transcription by suppressing the transactivator function of the CLOCK:BMAL1 heterodimer directly (physical model) and by facilit...

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Detalles Bibliográficos
Autores principales:	Ye, Rui, Selby, Christopher P., Ozturk, Nuri, Annayev, Yunus, Sancar, Aziz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138243/ https://www.ncbi.nlm.nih.gov/pubmed/21613214 http://dx.doi.org/10.1074/jbc.M111.254680

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