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Regulation of opioid receptor signalling: Implications for the development of analgesic tolerance
Opiate drugs are the most effective analgesics available but their clinical use is restricted by severe side effects. Some of these undesired actions appear after repeated administration and are related to adaptive changes directed at counteracting the consequences of sustained opioid receptor activ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138391/ https://www.ncbi.nlm.nih.gov/pubmed/21663702 http://dx.doi.org/10.1186/1756-6606-4-25 |