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Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection

Due to its hemostatic effect, local epinephrine has been used to minimize mucosal bleeding during endoscopic submucosal dissection (ESD), but its clinical benefit remains unclear. On the other hand, several adverse events deemed to be caused by epinephrine have been observed during ESD. A 73-year-ol...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Hun, Park, Moo In, Park, Seun Ja, Moon, Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138412/
https://www.ncbi.nlm.nih.gov/pubmed/21811546
http://dx.doi.org/10.4021/jocmr565w
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author Kim, Hyung Hun
Park, Moo In
Park, Seun Ja
Moon, Won
author_facet Kim, Hyung Hun
Park, Moo In
Park, Seun Ja
Moon, Won
author_sort Kim, Hyung Hun
collection PubMed
description Due to its hemostatic effect, local epinephrine has been used to minimize mucosal bleeding during endoscopic submucosal dissection (ESD), but its clinical benefit remains unclear. On the other hand, several adverse events deemed to be caused by epinephrine have been observed during ESD. A 73-year-old woman developed myocardial infarction after ESD for a large rectal adenoma, and an 80-year-old woman developed abrupt chest tightness during ESD. In both patients, changes on electrocardiogram and elevated cardiac markers provided evidence of myocardial ischemia. The patients were transferred to the cardiac care unit and recovered completely. Up to our knowledge this is the first report of myocardial infarction thought to be provoked by submucosal epinephrine injection during ESD. KEYWORDS: Adenoma; Colon; Endoscopic surgical procedure; Epinephrine; Myocardial infarction
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spelling pubmed-31384122011-08-02 Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection Kim, Hyung Hun Park, Moo In Park, Seun Ja Moon, Won J Clin Med Res Case Report Due to its hemostatic effect, local epinephrine has been used to minimize mucosal bleeding during endoscopic submucosal dissection (ESD), but its clinical benefit remains unclear. On the other hand, several adverse events deemed to be caused by epinephrine have been observed during ESD. A 73-year-old woman developed myocardial infarction after ESD for a large rectal adenoma, and an 80-year-old woman developed abrupt chest tightness during ESD. In both patients, changes on electrocardiogram and elevated cardiac markers provided evidence of myocardial ischemia. The patients were transferred to the cardiac care unit and recovered completely. Up to our knowledge this is the first report of myocardial infarction thought to be provoked by submucosal epinephrine injection during ESD. KEYWORDS: Adenoma; Colon; Endoscopic surgical procedure; Epinephrine; Myocardial infarction Elmer Press 2011-06 2011-05-19 /pmc/articles/PMC3138412/ /pubmed/21811546 http://dx.doi.org/10.4021/jocmr565w Text en Copyright © 2011, Kim et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Hyung Hun
Park, Moo In
Park, Seun Ja
Moon, Won
Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title_full Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title_fullStr Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title_full_unstemmed Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title_short Myocardial Infarction Thought to be Provoked by Local Epinephrine Injection During Endoscopic Submucosal Dissection
title_sort myocardial infarction thought to be provoked by local epinephrine injection during endoscopic submucosal dissection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138412/
https://www.ncbi.nlm.nih.gov/pubmed/21811546
http://dx.doi.org/10.4021/jocmr565w
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