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A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells
In normal growth and development, apoptosis is necessary to shape the central nervous system and to eliminate excess neurons which are not required for innervation. In some diseases, however, apoptosis can be either overactive as in some neurodegenerative disorders or severely attenuated as in the s...
Autores principales: | Rochira, Jennifer A., Matluk, Nicholas N., Adams, Tamara L., Karaczyn, Aldona A., Oxburgh, Leif, Hess, Samuel T., Verdi, Joseph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138748/ https://www.ncbi.nlm.nih.gov/pubmed/21789165 http://dx.doi.org/10.1371/journal.pone.0020659 |
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