Polymorphisms in the Mn-SOD and EC-SOD Genes and Their Relationship to Diabetic Neuropathy in Type 1 Diabetes Mellitus

BACKGROUND: Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN). Antioxidant enzymes may protect against the rapid onset and progression of DN, by reducing the excess of OFR and peroxide. Mutatio...

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Detalles Bibliográficos
Autores principales: Chistyakov, Dimitry A, Savost'anov, Kirill V, Zotova, Elena V, Nosikov, Valery V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31388/
https://www.ncbi.nlm.nih.gov/pubmed/11299047
http://dx.doi.org/10.1186/1471-2350-2-4

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