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Manganese Induces Oxidative Stress, Redox State Unbalance and Disrupts Membrane Bound ATPases on Murine Neuroblastoma Cells In Vitro: Protective Role of Silymarin

Manganese (Mn) is an essential trace element required for ubiquitous enzymatic reactions. Chronic overexposure to this metal may promote potent neurotoxic effects. The mechanism of Mn toxicity is not well established, but several studies indicate that oxidative stress play major roles in the Mn-indu...

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Detalles Bibliográficos
Autores principales: Chtourou, Yassine, Trabelsi, Khaled, Fetoui, Hamadi, Mkannez, Ghada, Kallel, Héla, Zeghal, Najiba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139064/
https://www.ncbi.nlm.nih.gov/pubmed/21533646
http://dx.doi.org/10.1007/s11064-011-0483-5