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Manganese Induces Oxidative Stress, Redox State Unbalance and Disrupts Membrane Bound ATPases on Murine Neuroblastoma Cells In Vitro: Protective Role of Silymarin
Manganese (Mn) is an essential trace element required for ubiquitous enzymatic reactions. Chronic overexposure to this metal may promote potent neurotoxic effects. The mechanism of Mn toxicity is not well established, but several studies indicate that oxidative stress play major roles in the Mn-indu...
Autores principales: | Chtourou, Yassine, Trabelsi, Khaled, Fetoui, Hamadi, Mkannez, Ghada, Kallel, Héla, Zeghal, Najiba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139064/ https://www.ncbi.nlm.nih.gov/pubmed/21533646 http://dx.doi.org/10.1007/s11064-011-0483-5 |
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