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Synthetic Pre-miRNA-Based shRNA as Potent RNAi Triggers

RNA interference (RNAi) is a powerful tool for studying gene function owing to the ease with which it can selectively silence genes of interest, and it has also attracted attention because of its potential for therapeutic applications. Chemically synthesized small interfering RNAs (siRNAs) and DNA v...

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Detalles Bibliográficos
Autores principales: Terasawa, Kazuya, Shimizu, Kazuharu, Tsujimoto, Gozoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139136/
https://www.ncbi.nlm.nih.gov/pubmed/21776374
http://dx.doi.org/10.4061/2011/131579