Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis

Recent reports have emerged suggesting that multiple sclerosis (MS) may be due to abnormal venous outflow from the central nervous system, termed chronic cerebrospinal venous insufficiency (CCSVI). These reports have generated strong interest and controversy over the prospect of a treatable cause of...

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Autores principales: Lazzaro, Marc A., Zaidat, Osama O., Mueller-Kronast, Nils, Taqi, Muhammad A., Woo, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139170/
https://www.ncbi.nlm.nih.gov/pubmed/21808631
http://dx.doi.org/10.3389/fneur.2011.00044
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author Lazzaro, Marc A.
Zaidat, Osama O.
Mueller-Kronast, Nils
Taqi, Muhammad A.
Woo, Douglas
author_facet Lazzaro, Marc A.
Zaidat, Osama O.
Mueller-Kronast, Nils
Taqi, Muhammad A.
Woo, Douglas
author_sort Lazzaro, Marc A.
collection PubMed
description Recent reports have emerged suggesting that multiple sclerosis (MS) may be due to abnormal venous outflow from the central nervous system, termed chronic cerebrospinal venous insufficiency (CCSVI). These reports have generated strong interest and controversy over the prospect of a treatable cause of this chronic debilitating disease. This review aims to describe the proposed association between CCSVI and MS, summarize the current data, and discuss the role of endovascular therapy and the need for rigorous randomized clinical trials to evaluate this association and treatment.
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spelling pubmed-31391702011-08-01 Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis Lazzaro, Marc A. Zaidat, Osama O. Mueller-Kronast, Nils Taqi, Muhammad A. Woo, Douglas Front Neurol Neuroscience Recent reports have emerged suggesting that multiple sclerosis (MS) may be due to abnormal venous outflow from the central nervous system, termed chronic cerebrospinal venous insufficiency (CCSVI). These reports have generated strong interest and controversy over the prospect of a treatable cause of this chronic debilitating disease. This review aims to describe the proposed association between CCSVI and MS, summarize the current data, and discuss the role of endovascular therapy and the need for rigorous randomized clinical trials to evaluate this association and treatment. Frontiers Research Foundation 2011-07-14 /pmc/articles/PMC3139170/ /pubmed/21808631 http://dx.doi.org/10.3389/fneur.2011.00044 Text en Copyright © 2011 Lazzaro, Zaidat, Mueller-Kronast, Taqi and Woo. http://www.frontiersin.org/licenseagreement This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.
spellingShingle Neuroscience
Lazzaro, Marc A.
Zaidat, Osama O.
Mueller-Kronast, Nils
Taqi, Muhammad A.
Woo, Douglas
Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title_full Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title_fullStr Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title_full_unstemmed Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title_short Endovascular Therapy for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis
title_sort endovascular therapy for chronic cerebrospinal venous insufficiency in multiple sclerosis
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139170/
https://www.ncbi.nlm.nih.gov/pubmed/21808631
http://dx.doi.org/10.3389/fneur.2011.00044
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