Cargando…

Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

A recent paper reported that Aβ oligomer causes neuronal cell death through the phosphatidylinositol-3-OH kinase (PI3K)-Akt-mTOR signaling pathway. Intraneuronal Aβ, a main pathological finding of Alzheimer's disease (AD), is also known as inhibiting activation of Akt. This study aims to invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shibata, Nobuto, Ohnuma, Tohru, Kuerban, Bolati, Komatsu, Miwa, Baba, Hajime, Arai, Heii
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139182/ https://www.ncbi.nlm.nih.gov/pubmed/21785701 http://dx.doi.org/10.4061/2011/762471

Ejemplares similares

Genetic Association between Neurotrophin-3 Polymorphisms and Alzheimer's Disease in Japanese Patients
por: Nagata, Tomoyuki, et al.
Publicado: (2013)

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia
por: Shibata, Nobuto, et al.
Publicado: (2013)

Age-Related Association between Apolipoprotein E ε4 and Cognitive Function in Japanese Patients with Alzheimer's Disease
por: Nagata, Tomoyuki, et al.
Publicado: (2013)

Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease
por: Nagata, Tomoyuki, et al.
Publicado: (2015)

No Associations Found between PGBD1 and the Age of Onset in Japanese Patients Diagnosed with Sporadic Alzheimer's Disease
por: Ohnuma, Tohru, et al.
Publicado: (2012)

Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population
por: Suzuki, Ayako, et al.
Publicado: (2016)

Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer’s disease: a prospective, open-label pilot study
por: Ohnuma, Tohru, et al.
Publicado: (2016)

Genetic or Psychogenic? A Case Study of “Folie à Quatre” Including Twins
por: Ohnuma, Tohru, et al.
Publicado: (2015)

Development of Biomarkers Based on DNA Methylation in the NCAPH2/LMF2 Promoter Region for Diagnosis of Alzheimer’s Disease and Amnesic Mild Cognitive Impairment
por: Kobayashi, Nobuyuki, et al.
Publicado: (2016)

Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment
por: Kobayashi, Nobuyuki, et al.
Publicado: (2016)

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia
por: Ohnuma, Tohru, et al.
Publicado: (2018)

Supplementation with Matured Hop Bitter Acids Improves Cognitive Performance and Mood State in Healthy Older Adults with Subjective Cognitive Decline
por: Fukuda, Takafumi, et al.
Publicado: (2020)

Donepezil may reduce the risk of comorbidities in patients with Alzheimer's disease: A large-scale matched case-control analysis in Japan
por: Kobayashi, Hiroyuki, et al.
Publicado: (2018)

PS157. Impact of benzodiazepine on cognition of remitted depression
por: Ishijima, Satoko, et al.
Publicado: (2016)

PS82. Does Serum Amyloid ß-Protein predict the Response to Antidepressant treatment in Major Depression?
por: Inoue, Megumi, et al.
Publicado: (2016)

PS95. Cognitive impairment of remitted depression in medication with anticholinergic activity
por: Maeshima, Hitoshi, et al.
Publicado: (2016)

Serum brain-derived neurotrophic factor levels and personality traits in patients with major depression
por: Nomoto, Hiroshi, et al.
Publicado: (2015)

LncRNA SNHG10 suppresses the development of doxorubicin resistance by downregulating miR-302b in triple-negative breast cancer
por: Aini, Shataer, et al.
Publicado: (2022)

LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population
por: Mori, Kazuhiko, et al.
Publicado: (2008)

Mixed Alzheimer's and Lewy-related Pathology Can Cause Corticobasal Syndrome with Visual Hallucinations
por: Kasanuki, Koji, et al.
Publicado: (2019)

Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population
por: Zhao, Chenxi, et al.
Publicado: (2014)

Writing Impairments in Japanese Patients with Mild Cognitive Impairment and with Mild Alzheimer's Disease
por: Hayashi, Atsuko, et al.
Publicado: (2015)

Serotonin transporter gene polymorphism may be associated with functional dyspepsia in a Japanese population
por: Toyoshima, Fumihiko, et al.
Publicado: (2011)

Importance of Rare DPYD Genetic Polymorphisms for 5-Fluorouracil Therapy in the Japanese Population
por: Hishinuma, Eiji, et al.
Publicado: (2022)

Impact of anti-doping education and doping control experience on anti-doping knowledge in Japanese university athletes: a cross-sectional study
por: Murofushi, Yuka, et al.
Publicado: (2018)

Population pharmacokinetics of roxadustat in Japanese dialysis‐dependent chronic kidney disease patients with anaemia
por: Takada, Akitsugu, et al.
Publicado: (2021)

Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population
por: Kiyohara, Chikako, et al.
Publicado: (2011)

ORAI1 Genetic Polymorphisms Associated with the Susceptibility of Atopic Dermatitis in Japanese and Taiwanese Populations
por: Chang, Wei-Chiao, et al.
Publicado: (2012)

Association of matrix metalloproteinase 8 genetic polymorphisms with bronchial asthma in a Japanese population
por: Shimoda, Terufumi, et al.
Publicado: (2013)

Association of STAT4 Polymorphisms with Susceptibility to Type-1 Autoimmune Hepatitis in the Japanese Population
por: Migita, Kiyoshi, et al.
Publicado: (2013)

Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population
por: Nishida, Yuichiro, et al.
Publicado: (2016)

XRCC1 Arg194Trp polymorphism, risk of nonmelanoma skin cancer and extramammary Paget’s disease in a Japanese population
por: Chiyomaru, Koji, et al.
Publicado: (2012)

Role of genetic polymorphisms of the RNASEL gene on familial prostate cancer risk in a Japanese population
por: Nakazato, H, et al.
Publicado: (2003)

Genetic polymorphisms of enzyme proteins and transporters related to methotrexate response and pharmacokinetics in a Japanese population
por: Hashiguchi, Masayuki, et al.
Publicado: (2016)

Lack of replication of associations between multiple genetic polymorphisms and endurance athlete status in Japanese population
por: Yvert, Thomas, et al.
Publicado: (2016)

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease
por: Kakuda, Nobuto, et al.
Publicado: (2012)

MUTYH Gln324His gene polymorphism and genetic susceptibility for lung cancer in a Japanese population
por: Miyaishi, Aiko, et al.
Publicado: (2009)

Genetic Polymorphisms of Molecules Associated with Innate Immune Responses, TRL2 and MBL2 Genes in Japanese Subjects with Functional Dyspepsia
por: Tahara, Tomomitsu, et al.
Publicado: (2010)

Genetic characterization and pathogenicity of Japanese porcine deltacoronavirus
por: Suzuki, Tohru, et al.
Publicado: (2018)

The relationship between health-related quality of life and social networks among Japanese family caregivers for people with disabilities
por: Arai, Hirokazu, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_lcikj955mq50h3nrquug4qglsa