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Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies

Besides fluorine, oxygen is the most electronegative element with the highest reduction potential in biological systems. Metabolic pathways in mammalian cells utilize oxygen as the ultimate oxidizing agent to harvest free energy. They are very efficient, but not without risk of generating various ox...

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Detalles Bibliográficos
Autores principales: Facecchia, Katie, Fochesato, Lee-Anne, Ray, Sidhartha D., Stohs, Sidney J., Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139184/
https://www.ncbi.nlm.nih.gov/pubmed/21785590
http://dx.doi.org/10.1155/2011/683728