Proinflammatory Protein CARD9 Is Essential for Infiltration of Monocytic Fibroblast Precursors and Cardiac Fibrosis Caused by Angiotensin II Infusion

BACKGROUND: Angiotensin II (Ang II)–induced cardiac remodeling with the underlying mechanisms involving inflammation and fibrosis has been well documented. Cytosolic adaptor caspase recruitment domain 9 (CARD9) has been implicated in the innate immune response. We aimed to examine the role of CARD9...

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Detalles Bibliográficos
Autores principales: Ren, Jingyuan, Yang, Min, Qi, Guanming, Zheng, Jiao, Jia, Lixin, Cheng, Jizhong, Tian, Cui, Li, Huihua, Lin, Xin, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Heart
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139445/
https://www.ncbi.nlm.nih.gov/pubmed/21436792
http://dx.doi.org/10.1038/ajh.2011.42

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