Cargando…
Phosphorylation of AKT: a Mutational Analysis
Akt (cellular homolog of murine thymoma virus akt8 oncogene) is an essential component of the PI3K (phosphatidylinositol 3-kinase) pathway. Its activity is stimulated by receptor tyrosine kinases and G-protein coupled receptors and plays a critical role in the regulation of cell proliferation, diffe...
Autores principales: | Hart, Jonathan R., Vogt, Peter K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139455/ https://www.ncbi.nlm.nih.gov/pubmed/21670491 |
Ejemplares similares
-
Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest
por: Shouse, Geoffrey, et al.
Publicado: (2016) -
Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85α and p85β
por: Ito, Yoshihiro, et al.
Publicado: (2017) -
Filamin A phosphorylation by Akt promotes cell migration in response to arsenic
por: Li, Lingzhi, et al.
Publicado: (2015) -
Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT
por: Xu, Yi, et al.
Publicado: (2018) -
HDAC10 promotes lung cancer proliferation via AKT phosphorylation
por: Yang, Yiwei, et al.
Publicado: (2016)