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Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention
Alzheimer disease (AD) is multi-factorial and heterogeneous. Independent of the aetiology, this disease is characterized clinically by chronic and progressive dementia and histopathologically by neurofibrillary degeneration of abnormally hyperphosphorylated tau seen as intraneuronal neurofibrillary...
Autores principales: | Iqbal, K, Grundke-Iqbal, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139457/ https://www.ncbi.nlm.nih.gov/pubmed/18194444 http://dx.doi.org/10.1111/j.1582-4934.2008.00225.x |
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