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Predictors of weight loss and maintenance in patients treated with antiobesity drugs

BACKGROUND: The prevalence of obesity and related diseases has increased enormously in the last few decades, becoming a very important medical and social issue. Because of the increasing number of people who need weight loss therapies and the high costs associated with these, the search for reliable...

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Detalles Bibliográficos
Autores principales: Guaraldi, Federica, Pagotto, Uberto, Pasquali, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139531/
https://www.ncbi.nlm.nih.gov/pubmed/21792322
http://dx.doi.org/10.2147/DMSO.S19197
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author Guaraldi, Federica
Pagotto, Uberto
Pasquali, Renato
author_facet Guaraldi, Federica
Pagotto, Uberto
Pasquali, Renato
author_sort Guaraldi, Federica
collection PubMed
description BACKGROUND: The prevalence of obesity and related diseases has increased enormously in the last few decades, becoming a very important medical and social issue. Because of the increasing number of people who need weight loss therapies and the high costs associated with these, the search for reliable predictors of success for weight loss and weight maintenance treatments has become a priority. OBJECTIVE: A literature review was undertaken to identify possible predictors of outcome of weight loss and weight maintenance in patients treated with antiobesity drugs. RESULTS: For the majority of variables, published data are not sufficient to define their role on final outcomes. Among all considered factors, only early response to treatment appeared to be a reliable positive predictor, and diabetes a negative predictor of weight loss and maintenance. CONCLUSION: To date, no definitive results have been obtained. Due to the great benefits of reliable predictors of outcome associated to currently available antiobesity drugs and those under development, identifying these predictors has to be supported and encouraged.
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spelling pubmed-31395312011-07-26 Predictors of weight loss and maintenance in patients treated with antiobesity drugs Guaraldi, Federica Pagotto, Uberto Pasquali, Renato Diabetes Metab Syndr Obes Review BACKGROUND: The prevalence of obesity and related diseases has increased enormously in the last few decades, becoming a very important medical and social issue. Because of the increasing number of people who need weight loss therapies and the high costs associated with these, the search for reliable predictors of success for weight loss and weight maintenance treatments has become a priority. OBJECTIVE: A literature review was undertaken to identify possible predictors of outcome of weight loss and weight maintenance in patients treated with antiobesity drugs. RESULTS: For the majority of variables, published data are not sufficient to define their role on final outcomes. Among all considered factors, only early response to treatment appeared to be a reliable positive predictor, and diabetes a negative predictor of weight loss and maintenance. CONCLUSION: To date, no definitive results have been obtained. Due to the great benefits of reliable predictors of outcome associated to currently available antiobesity drugs and those under development, identifying these predictors has to be supported and encouraged. Dove Medical Press 2011-06-20 /pmc/articles/PMC3139531/ /pubmed/21792322 http://dx.doi.org/10.2147/DMSO.S19197 Text en © 2011 Guaraldi et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Guaraldi, Federica
Pagotto, Uberto
Pasquali, Renato
Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_full Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_fullStr Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_full_unstemmed Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_short Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_sort predictors of weight loss and maintenance in patients treated with antiobesity drugs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139531/
https://www.ncbi.nlm.nih.gov/pubmed/21792322
http://dx.doi.org/10.2147/DMSO.S19197
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