Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide

BACKGROUND: Hypertension is, amongst others, characterized by endothelial dysfunction and vascular remodeling. As sphingolipids have been implicated in both the regulation of vascular contractility and growth, we investigated whether sphingolipid biology is altered in hypertension and whether this i...

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Detalles Bibliográficos
Autores principales: Spijkers, Léon J. A., van den Akker, Rob F. P., Janssen, Ben J. A., Debets, Jacques J., De Mey, Jo G. R., Stroes, Erik S. G., van den Born, Bert-Jan H., Wijesinghe, Dayanjan S., Chalfant, Charles E., MacAleese, Luke, Eijkel, Gert B., Heeren, Ron M. A., Alewijnse, Astrid E., Peters, Stephan L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139577/
https://www.ncbi.nlm.nih.gov/pubmed/21818267
http://dx.doi.org/10.1371/journal.pone.0021817

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