Cargando…

In vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-Length (YAC128) Transgenic Mouse Models of Huntington's Disease

Huntington's disease (HD) is characterized by numerous alterations within the corticostriatal circuitry. The striatum is innervated by a dense array of dopaminergic (DA) terminals and these DA synapses are critical to the proper execution of motor functions. As motor disturbances are prevalent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Callahan, Joshua W., Abercrombie, Elizabeth D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139944/ https://www.ncbi.nlm.nih.gov/pubmed/21811446 http://dx.doi.org/10.3389/fnsys.2011.00061

Ejemplares similares

Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease
por: de Paula Nascimento-Castro, Cristine, et al.
Publicado: (2018)

Transplantation of patient-derived adipose stem cells in YAC128 Huntington's disease transgenic mice
por: Im, Wooseok, et al.
Publicado: (2010)

Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington’s Disease
por: de Paula Nascimento-Castro, Cristine, et al.
Publicado: (2022)

C57BL/6 Background Attenuates mHTT Toxicity in the Striatum of YAC128 Mice
por: Back, Michaela K., et al.
Publicado: (2021)

Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
por: Ellrichmann, Gisa, et al.
Publicado: (2011)

Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice
por: Berggren, Kiersten L., et al.
Publicado: (2016)

Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease
por: Bečanović, Kristina, et al.
Publicado: (2021)

Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington’s Disease Effects in YAC128 Mice
por: Plácido, Evelini, et al.
Publicado: (2023)

Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence
por: Bayram-Weston, Zubeyde, et al.
Publicado: (2015)

AAV-Dominant Negative Tumor Necrosis Factor (DN-TNF) Gene Transfer to the Striatum Does Not Rescue Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease
por: Alto, Laura Taylor, et al.
Publicado: (2014)

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease
por: Carroll, Jeffrey B, et al.
Publicado: (2011)

Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
por: Teo, Roy Tang Yi, et al.
Publicado: (2016)

Author Correction: Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease
por: Bečanović, Kristina, et al.
Publicado: (2021)

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease
por: Schmidt, Mandi E., et al.
Publicado: (2018)

Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease
por: Li, Endan, et al.
Publicado: (2020)

Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
por: Garcia-Miralles, Marta, et al.
Publicado: (2016)

A CAG repeat-targeting artificial miRNA lowers the mutant huntingtin level in the YAC128 model of Huntington's disease
por: Kotowska-Zimmer, Anna, et al.
Publicado: (2022)

Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington’s Disease
por: Czeredys, Magdalena, et al.
Publicado: (2018)

Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease
por: Van Raamsdonk, Jeremy M, et al.
Publicado: (2006)

Differential Synaptic and Extrasynaptic Glutamate-Receptor Alterations in Striatal Medium-Sized Spiny Neurons of Aged YAC128 Huntington’s Disease Mice
por: Botelho, Eliã P., et al.
Publicado: (2014)

Correction: Differential Synaptic and Extrasynaptic Glutamate-Receptor Alterations in Striatal Medium-Sized Spiny Neurons of Aged YAC128 Huntington's Disease Mice
Publicado: (2017)

DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
por: Schmidt, Mandi E., et al.
Publicado: (2020)

In Vivo Roles of a Patient-Derived Induced Pluripotent Stem Cell Line (HD72-iPSC) in the YAC128 Model of Huntington’s Disease
por: Jeon, Iksoo, et al.
Publicado: (2014)

Solid Lipid Curcumin Particles Protect Medium Spiny Neuronal Morphology, and Reduce Learning and Memory Deficits in the YAC128 Mouse Model of Huntington’s Disease
por: Gharaibeh, Abeer, et al.
Publicado: (2020)

microRNA-128a dysregulation in transgenic Huntington’s disease monkeys
por: Kocerha, Jannet, et al.
Publicado: (2014)

Induced Pluripotent Stem Cell-Derived Neural Stem Cell Transplantations Reduced Behavioral Deficits and Ameliorated Neuropathological Changes in YAC128 Mouse Model of Huntington's Disease
por: Al-Gharaibeh, Abeer, et al.
Publicado: (2017)

Human iPSC‐derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model
por: Park, Hyun Jung, et al.
Publicado: (2021)

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models
por: Träger, Ulrike, et al.
Publicado: (2015)

Cellular, Molecular and Functional Characterisation of YAC Transgenic Mouse Models of Friedreich Ataxia
por: Anjomani Virmouni, Sara, et al.
Publicado: (2014)

Dysfunctional mitochondrial respiration in the striatum of the Huntington’s disease transgenic R6/2 mouse model
por: Aidt, Frederik Heurlin, et al.
Publicado: (2013)

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse
por: Kusko, Rebecca, et al.
Publicado: (2018)

Metabolomics Study of Serum Samples of β-YAC Transgenic Mice Treated with Tenofovir Disoproxil Fumarate
por: Kumari, Sindhia, et al.
Publicado: (2022)

Human Multipotent Stromal Cells (MSCs) Increase Neurogenesis and Decrease Atrophy of the Striatum in a Transgenic Mouse Model for Huntington's Disease
por: Snyder, Brooke R., et al.
Publicado: (2010)

Acetylcholine waves and dopamine release in the striatum
por: Matityahu, Lior, et al.
Publicado: (2023)

The dopamine neuron synaptic map in the striatum
por: Chuhma, Nao, et al.
Publicado: (2023)

Identification of Genomic Regions Regulating Pax6 Expression in Embryonic Forebrain Using YAC Reporter Transgenic Mouse Lines
por: Mi, Da, et al.
Publicado: (2013)

Evaluation of D1 and D2 Dopamine Receptor Segregation in the Developing Striatum Using BAC Transgenic Mice
por: Thibault, Dominic, et al.
Publicado: (2013)

Huntington disease: a single-gene degenerative disorder of the striatum
por: Nopoulos, Peggy C.
Publicado: (2016)

The specific role of the striatum in interval timing: The Huntington’s disease model
por: Lemoine, Laurie, et al.
Publicado: (2021)

Sub-Second Dopamine Detection in Human Striatum
por: Kishida, Kenneth T., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_u8r1vd6amfg60fcdqnt3kcscbc