Formulating multicellular models of metabolism in tissues: application to energy metabolism in the human brain

A workflow is presented that integrates gene expression data, proteomic data, and literature-based manual curation to construct multicellular, tissue-specific models of human brain energy metabolism that recapitulate metabolic interactions between astrocytes and various neuron types. Three analyses...

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Detalles Bibliográficos
Autores principales: Lewis, Nathan E., Schramm, Gunnar, Bordbar, Aarash, Schellenberger, Jan, Andersen, Michael Paul, Cheng, Jeffrey K., Patel, Nilam, Yee, Alex, Lewis, Randall A., Eils, Roland, König, Rainer, Palsson, Bernhard Ø.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140076/
https://www.ncbi.nlm.nih.gov/pubmed/21102456
http://dx.doi.org/10.1038/nbt.1711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140076/
https://www.ncbi.nlm.nih.gov/pubmed/21102456
http://dx.doi.org/10.1038/nbt.1711

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