Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient

We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule...

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Detalles Bibliográficos
Autores principales: Shirali, Arun, Kini, Jyoti, Vupputuri, Anjith, Kuruvila, Maria, Prabhu, M. Venkatraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140147/
https://www.ncbi.nlm.nih.gov/pubmed/21808435
http://dx.doi.org/10.4103/2589-0557.68999
Descripción
Sumario:We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

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