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Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats

Learning and memory impairments occurring with Alzheimer's disease (AD) are associated with degeneration of the basal forebrain cholinergic neurons (BFCNs). BFCNs extend their axons to the hippocampus where they bind nerve growth factor (NGF) which is retrogradely transported to the cell body....

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Detalles Bibliográficos
Autores principales: Fortress, Ashley M., Buhusi, Mona, Helke, Kris L., Granholm, Ann-Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140182/
https://www.ncbi.nlm.nih.gov/pubmed/21785728
http://dx.doi.org/10.4061/2011/460543