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T Cell Recognition of Autoantigens in Human Type 1 Diabetes: Clinical Perspectives

Type 1 diabetes (T1D) is an autoimmune disease driven by the activation of lymphocytes against pancreatic β-cells. Among β-cell autoantigens, preproinsulin has been ascribed a key role in the T1D process. The successive steps that control the activation of autoreactive lymphocytes have been extensiv...

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Detalles Bibliográficos
Autores principales:	Mallone, Roberto, Brezar, Vedran, Boitard, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140193/ https://www.ncbi.nlm.nih.gov/pubmed/21785617 http://dx.doi.org/10.1155/2011/513210

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