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Bucindolol: A Pharmacogenomic Perspective on Its Use in Chronic Heart Failure

Bucindolol is a non-selective β-adrenergic receptor blocker with α-1 blocker properties and mild intrinsic sympatholytic activity. The Beta-Blocker Evaluation of Survival Trial (BEST), which is the largest clinical trial of bucindolol in patients with heart failure, was terminated prematurely and fa...

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Detalles Bibliográficos
Autores principales: Smart, Neil A., Kwok, Nigel, Holland, David J., Jayasighe, Rohan, Giallauria, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140276/
https://www.ncbi.nlm.nih.gov/pubmed/21792345
http://dx.doi.org/10.4137/CMC.S4309