Cargando…
Bucindolol: A Pharmacogenomic Perspective on Its Use in Chronic Heart Failure
Bucindolol is a non-selective β-adrenergic receptor blocker with α-1 blocker properties and mild intrinsic sympatholytic activity. The Beta-Blocker Evaluation of Survival Trial (BEST), which is the largest clinical trial of bucindolol in patients with heart failure, was terminated prematurely and fa...
Autores principales: | Smart, Neil A., Kwok, Nigel, Holland, David J., Jayasighe, Rohan, Giallauria, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140276/ https://www.ncbi.nlm.nih.gov/pubmed/21792345 http://dx.doi.org/10.4137/CMC.S4309 |
Ejemplares similares
-
A Personalized BEST: Characterization of Latent Clinical Classes of Nonischemic Heart Failure That Predict Outcomes and Response to Bucindolol
por: Kao, David P., et al.
Publicado: (2012) -
Combinatorial Pharmacogenetic Interactions of Bucindolol and β(1), α(2C) Adrenergic Receptor Polymorphisms
por: O'Connor, Christopher M., et al.
Publicado: (2012) -
Crystal Structures of a Stabilized β(1)-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol
por: Warne, Tony, et al.
Publicado: (2012) -
Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine
por: de Lima-Seolin, Bruna Gazzi, et al.
Publicado: (2019) -
Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling
por: Femminella, Grazia Daniela, et al.
Publicado: (2014)