Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response

Development of targeted therapy for hepatocellular carcinoma (HCC) remains a major challenge. We have recently identified an elevated expression of the fifth subunit of COP9 signalosome (CSN5) in early HCC as compared to dysplastic stage. In the present study, we explored the possibility of CSN5 bei...

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Detalles Bibliográficos
Autores principales: Lee, Y-H, Judge, AD, Seo, D, Kitade, M, Gómez-Quiroz, LE, Ishikawa, T, Andersen, JB, Kim, B-K, Marquardt, JU, Raggi, C, Avital, I, Conner, EA, MacLachlan, I, Factor, VM, Thorgeirsson, SS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140552/
https://www.ncbi.nlm.nih.gov/pubmed/21499307
http://dx.doi.org/10.1038/onc.2011.126

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