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Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

There has been growing interest among the public and scientists in dichloroacetate as a potential anticancer drug. Credible evidence exists for the antitumor activity of this compound, but high concentrations are needed for significant therapeutic effect. Unfortunately, these high concentrations pro...

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Detalles Bibliográficos
Autores principales: Babu, Ellappan, Ramachandran, Sabarish, CoothanKandaswamy, Veena, Elangovan, Selvakumar, Prasad, Puttur D., Ganapathy, Vadivel, Thangaraju, Muthusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140604/
https://www.ncbi.nlm.nih.gov/pubmed/21499304
http://dx.doi.org/10.1038/onc.2011.113